His career as a performer has been greatly enhanced by his composing activities, a vital part of nearly all of his live concerts and recordings. In 2003, Hersch created Leaves of Grass (Palmetto presented in March 2005 in a sold-out performance at Zankel Hall at Carnegie Hall as part of a six-city US tour. Hersch has toured with concert pianist Christopher O'Riley ("Heard Fresh: Music for Two Pianos") and he has also collaborated with artists ranging from Bill Frisell, Toots Thielemans and Charlie Haden to singers Renée Fleming, Norma Winstone and Audra McDonald. He has received commissions from The Gilmore Keyboard Festival, The Doris Duke Foundation, The Miller 1Theatre at Columbia University, The Gramercy Trio and The Brooklyn Youth Chorus. His solo piano compositions and chamber music are published by Edition Peters. Naxos Records has released Fred Hersch: Concert Music 2001-2006, a disc of his through-composed "classical" works.
Hersch is considered to be the most prolific and widely-praised solo jazz pianist of his generation. 2009 saw the release of his eighth solo disc Fred Hersch Plays Jobim on Sunnyside, cited as one of the Top Ten jazz releases of 2009 by NPR and by the Wall Street Journal. In 2006, Palmetto Records released the solo CD Fred Hersch in Amsterdam: Live at the Bimhuis; its release led to Hersch becoming the first pianist in the 70-year history of New York's legendary Village Vanguard to play an entire week as a solo pianist shortly after the disc's release. In addition, he leads a trio, a quintet and has ongoing special collaborations with jazz and classical instrumentalists and vocalists around the world. A recent project features an unconventional line-up of piano, trumpet, voice, and percussion; The Fred Hersch Pocket Orchestra: Live at Jazz Standard came out in April 2009 on Sunnyside Records. His latest release is The Fred Hersch Trio: Whirl, which came out in June 2010 on Palmetto Records.
Hersch has acted as a passionate spokesman and fund-raiser for AIDS services and education agencies since 1993. He has produced and performed on four benefit recordings and at numerous concerts for the charities Classical Action: Performing Arts Against AIDS and Broadway Cares/Equity Fights AIDS that have raised over $250,000 to date.
Hersch has been featured on CBS Sunday Morning with Dr. Billy Taylor and on a wide variety of National Public Radio programs including Fresh Air, Jazz Set, Studio 360, and Marian McPartland's Piano Jazz. Hersch has also been awarded a Rockefeller Fellowship, grants from The National Endowment for the Arts and Meet the Composer, and six composition residencies at The MacDowell Colony. He conducted a Professional Training Workshop for Young Musicians at The Weill Institute at Carnegie Hall in 2008 and was awarded the Branigan Lectureship at Indiana University in 2004. A committed educator, he has taught at The New School and Manhattan School of Music; he is currently a visiting professor at Western Michigan University and on the Jazz Studies faculty of the Juilliard School and The New England Conservatory.